Scientists create synthetic cell, version 1.0

[kennyc]

http://news.cnet.com/8301-17938_105-20005533-1.html

Scientists at the J. Craig Venter Institute have created a synthetic cell that can survive and reproduce itself according to an artificial DNA sequence, promising designer genomes with which researchers can produce sophisticated artificial organisms.

The new bacterial cell, "Mycoplasma mycoides JCVI-syn1.0," is the result of a 15-year, $30 million effort by genetics pioneer Craig Venter. The study, led by the institute's Dan Gibson, is reported in the May 21 edition of the journal Science.

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This is a big step!

Here's the link to the Science article: http://www.sciencemag.org/cgi/content/full/328/5981/958

"For 15 years, J. Craig Venter has chased a dream: to build a genome from scratch and use it to make synthetic life. Now, he and his team at the J. Craig Venter Institute (JCVI) in Rockville, Maryland, and San Diego, California, say they have realized that dream. In this week's Science Express (http://www.sciencemag.org/cgi/conten...cience.1190719), they describe the stepwise creation of a bacterial chromosome and the successful transfer of it into a bacterium, where it replaced the native DNA. Powered by the synthetic genome, that microbial cell began replicating and making a new set of proteins.

This is "a defining moment in the history of biology and biotechnology," says Mark Bedau, a philosopher at Reed College in Portland, Oregon, and editor of the scientific journal Artificial Life. "It represents an important technical milestone in the new field of synthetic genomics," says yeast biologist Jef Boeke of Johns Hopkins University School of Medicine in Baltimore, Maryland.

The synthetic genome created by Venter's team is almost identical to that of a natural bacterium. It was achieved at great expense, an estimated $40 million, and effort, 20 people working for more than a decade. Despite this success, creating heavily customized genomes, such as ones that make fuels or pharmaceuticals, and getting them to "boot" up the same way in a cell is not yet a reality. "There are great challenges ahead before genetic engineers can mix, match, and fully design an organism's genome from scratch," notes Paul Keim, a molecular geneticist at Northern Arizona University in Flagstaff."

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[WT Sharpe]

Originally Posted by kennyc

http://news.cnet.com/8301-17938_105-20005533-1.html

Scientists at the J. Craig Venter Institute have created a synthetic cell that can survive and reproduce itself according to an artificial DNA sequence, promising designer genomes with which researchers can produce sophisticated artificial organisms.

The new bacterial cell, "Mycoplasma mycoides JCVI-syn1.0," is the result of a 15-year, $30 million effort by genetics pioneer Craig Venter. The study, led by the institute's Dan Gibson, is reported in the May 21 edition of the journal Science.

....

This is a big step!

Here's the link to the Science article: http://www.sciencemag.org/cgi/content/full/328/5981/958

"For 15 years, J. Craig Venter has chased a dream: to build a genome from scratch and use it to make synthetic life. Now, he and his team at the J. Craig Venter Institute (JCVI) in Rockville, Maryland, and San Diego, California, say they have realized that dream. In this week's Science Express (http://www.sciencemag.org/cgi/conten...cience.1190719), they describe the stepwise creation of a bacterial chromosome and the successful transfer of it into a bacterium, where it replaced the native DNA. Powered by the synthetic genome, that microbial cell began replicating and making a new set of proteins.

This is "a defining moment in the history of biology and biotechnology," says Mark Bedau, a philosopher at Reed College in Portland, Oregon, and editor of the scientific journal Artificial Life. "It represents an important technical milestone in the new field of synthetic genomics," says yeast biologist Jef Boeke of Johns Hopkins University School of Medicine in Baltimore, Maryland.

The synthetic genome created by Venter's team is almost identical to that of a natural bacterium. It was achieved at great expense, an estimated $40 million, and effort, 20 people working for more than a decade. Despite this success, creating heavily customized genomes, such as ones that make fuels or pharmaceuticals, and getting them to "boot" up the same way in a cell is not yet a reality. "There are great challenges ahead before genetic engineers can mix, match, and fully design an organism's genome from scratch," notes Paul Keim, a molecular geneticist at Northern Arizona University in Flagstaff."

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Would you hate me if I was the one to tell you that ardeegee beat you in starting a thread on that?

"Venter Von Frankenstein"

https://www.mobileread.com/forums/sho...480#post919480

[kennyc]

Originally Posted by WT Sharpe

Would you hate me if I was the one to tell you that ardeegee beat you by two minutes is starting a thread on that?

https://www.mobileread.com/forums/sho...480#post919480

That sucks, but of course it would be him! And I saw it initially this morning and just now got around to checking it out to make sure it wasn't just more media hype.