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It would take years and the effect is much less in low power "White" LEDs than the room light kind. The eye is more sensitive to hue changes than brightness, so on an LED back lit LCD like a laptop or TV on 8 hrs+ a day you notice the colour shift first. Most front light eink would be having the LEDs running lower power than the same size LCD as the LCD colour panels lose up to 4/5ths of the light.
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