Calibre Locks Up

[Jafofubar]

Hello,
I have a Kobo Aura Second Edition. Thank you to Kovid and all the Calibre developers. I am having trouble using Calibre lately. It used to work perfectly. Now when I connect my Kobo it almost always comes up with an error saying Error Communicating With Device. At first (over a period of months) it just seemed to go slower and slower and now it won't communicate with my Kobo at all. I rebuilt my Kobo from factory defaults and uninstalled and reinstalled Calibre but still get the same thing. Calibre will open ok. When I click on the Preferences button, Calibre locks up and the only way for me to do anything with it after that, including closing it, is to go into Task Manager and "end task". Windows sees the Kobo fine. I'm using Windows 7 64bit with Calibre 64bit installed. Calibre does say "Connected to Kobo Aura Edition 2. The "Jobs" icon keeps spinning until after a long while and error comes up saying Error Comminicating with Device. I can't close that error box and I can't click on Details. All I can do is open task manager and End Task.
Does anyone have any ideas what is going wrong?
Thanks!

[theducks]

Is it Really locked up or is the focus NOW off screen.
That can happen, when you close calibre with 2 monitors and then take one away.

1)easy, connect the 2nd monitor, then move preferences and config dialogs to the main screen before exiting

2)harder. Rename(just in case it does not work) the (hidden) Calibre Configuration folder

C:\Users\<your logonname>\AppData\Roaming\calibre

Calibre will rebuild THE FACTORY DEFAULT. You lose your settings and plugins

[Jafofubar]

Originally Posted by theducks

Is it Really locked up or is the focus NOW off screen.
That can happen, when you close calibre with 2 monitors and then take one away.

1)easy, connect the 2nd monitor, then move preferences and config dialogs to the main screen before exiting

2)harder. Rename(just in case it does not work) the (hidden) Calibre Configuration folder

C:\Users\<your logonname>\AppData\Roaming\calibre

Calibre will rebuild THE FACTORY DEFAULT. You lose your settings and plugins

Thanks for your response. Yes, it was locked up. When I reinstalled Calibre, all the settings were still there so I wondered about hacking the registry to fully remove Calibre. Your way was much easier and it seems to have worked. I renamed that folder and tried again but it was still the same thing. So I renamed the folder, reset my Kobo to factory and started over. I imported the same library but now everything seems to be working. My guess is that something was wrong with one of the books on the Kobo and that was causing all the headaches. I got rid of two books that I suspect were causing the problem.
Everything looks good now.
Thanks a lot for your help!