I guess I am lucky as I have never had any problems with using all 3 programs on my XP computer. Sounds like there are issues with using the Sony software on Win 7.
I agree that you never need to install the Sony Software to use your reader but if your planning to buy ebooks from a majority of the ebookstores you'll need Adobe DE to download them even if you strip DRM so Calibre can process them.
If you are only reading free ebooks or buy from non-DRM places like Smashwords you'll only need Calibre
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