IF you can keep your computer from ever going to sleep or hibernating or any type of powering down, then yes, you could safely charge it. I find it's a losing battle on my netbook though (as well as older laptop), they always seem to hibernate anyway no matter how you set it. My desktop PCs though never sleep and I can safely charge all my USB electronics on them. If you're traveling, I'm going to assume you only have a netbook or laptop, and I don't think I'd trust them not going into hibernation.
It's possible a full charge will fix the problem, yes. It's a process of elimination trying various things that have been known to cause the issue you're having. No guarantee though that it will work, but certainly worth a try.
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