I have created a fairly large ePub file (5MB in size or so). The process I used was that I put the entire book together in MS Word 2011 and then exported as a filtered HTML file. I then loaded the HTML file into Calibre and converted it to ePub and mobi. The mobi file reads just fine in the eReaders that I've tried. When I load the ePub into my iPad and read it in iBooks, however, it has awkward spacing.
Any thoughts on what I could do to fix this? I'm somewhat at a loss and running out of ideas.