I nominate Shōgun by James Clavell.
Quote:
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Beginning in 1600 in feudal Japan, some months before the critical battle of Sekigahara, it gives an account of the rise of the daimyo "Toranaga" (based upon the actual Tokugawa Ieyasu) of the Shogunate, seen through the eyes of an English sailor whose fictional heroics are loosely based on William Adams's exploits.
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http://books.google.com/books?id=HZnINcS3RxYC
http://en.wikipedia.org/wiki/Sh%C5%8Dgun_(novel)