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I would argue yeah, I have glaucoma and am very near sighted so not greatest sample size but I can see the pixels of the HD Carta screens and it's why I did not go for the 10 inch readers as the 300 ppi on the t80d and the T80S I can already see them. My phones also have way more pixels and still I can see them sometimes but it's much harder ( v20 1440 x 2560 pixels, 16:9 ratio (~513 ppi density), (note 9 1440 x 2960 pixels, 18.5:9 ratio (~516 ppi density). The bigger the device the ppi it really should strive for. My X1C5 has a 1440p screen at 209 ppi and it's also very seeable if you run it at 1080p for instance. So for most it might not matter much but for a device in bed you might have closer to your face I prefer the higher ppi.
Malcolm
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