Many note-taking apps offer offline editing with a sync to the cloud, either on dropbox, iCloud or a dedicated server. But it's rarely perfect, either the app will try to sync even when you are offline and slow down until it finally realizes it can't, or if you have several devices there will be problems and conflicts with the sync. So far, Simplenotes seems to be working OK for me though. But I don't use it all that much, for me it's mostly a clipboard to transfer text between devices.
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