I don't know anything about furigana, but I do know that you have to be careful about the way you interpret the KPG. The KF8 devices use a custom version of webkit to render HTML and CSS. If you assume a slightly older version of webkit without javascript, you will have a decent idea of what you can do.
I would start with the assumption that if furigana was supported by webkit and you can embed a font with the proper support, it will work. You would have to use the @media {amzn-mobi} to control what happens with the downlevel version of your book.
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