What reader you buy can certainly affect your ease of transferring books to future devices, but it doesn't really have much influence on what books you can buy for your current device. Pretty much all commercial fiction eBooks are available in all the popular eBook formats - you'll find much the same books at the Sony eBook store as at the Mobipocket stores.
If you're a person who re-reads all their books and is therefore buying with the long-term future in mind, it's worth considering buying in something like LIT format, which can easily be converted to many other formats.
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