You have legitimate reasons for taking the approach you did. People may have good suggestions for making improvements, but don't cave in to pressure to make compromises just so it can be read on a small screen e-ink device.
You might consider looking at each image to see whether it needs to be large and detailed or whether it can be reduced in size and/or more heavily compressed. If the book needs to be 270 MB, then that is what it should be.
Walter Isaacson's Leonardo da Vinci can be over 170 MB.
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