It looks like Qt WebKit on windows doesn't like this font. You can see this for yourself by right clicking on any text, choosing "Inspect Element" then going to the Resources tab and then Frames->HTML file->Fonts and click on the three fonts, you will see that both the regular and italic variants are rendered as italic for some reason. Historically, Qt on windows has had issues with fonts that use a CFF table internally, although that was fixed a while ago.
This should automatically be fixed when calibre updates its version of Qt Webkit, but until then, I'm afraid there's not much that can be done, sorry.
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