I have the reader set to override the system brightness, with the level set as low as it goes. This provides a pleasant light level when reading during the day (indoors), and at night in bed with only a night light on. At this minimal brightness, I'm finding no eye strain, although I would say my eyes do find eink still gentler on the eyes.
In general, though, I'm pleased that I'm able to read comfortably on the Vox, as I was apprehensive about this aspect.
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