Jan, There are two things you can do to get more info about what's happening:
1) Open Console.app (it is in Utilities), and then try to start the Reader app. Look in Console if any error messages appear (maybe in `All Messages').
2) Start the Reader App from Terminal with this command:
"/Applications/Reader Library.app/Contents/MacOS/Reader Library"
(including the quotes!) Some error messages might come up in the Terminal window.
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