I just bought my Nook today and immediately set about to have a very protective cover. I took the
At A Glance planner cover that I used for my Sony 505 in the lightwedge cover because it zips all the way around. I then cut pieces of 1/8" thick Plexiglas to reinforce both front and back covers and sliced the foam from the nook box and inserted it into both sides in between the plexi and the inside of the cover. This way it is rigid to protect the screen yet padded to protect from shocks. My 505 died from a drop that didn't actually break the screen but messed up something in it. The only issue is the I would like to be able to put a tacky surface for the Nook to grab onto, kind of like the pads you can get for the dash of the car to hold phones and MP3 players, but without the added thickness. It is already as full as it can be safely.
Oh yeah, I also removed the metal part of the zipper from the pocket inside as well as the velcro tab that is meant to hold cards in.
So far, so good. Of course, I am always open to advice.