font sizes, spacing, margins, line lengths, it's all a personal preference.. maybe it's me, i've been reading since stone tablets, i regularly read technical documents where english is a second language and i'm happy they get sentence structure acceptable than to worry about formatting. everyone has their own preferences.
personally i prefer portrait mode, i find the 2 page landscape distracting and unnecessary. in a paper book, unless you can fold it back, you have to view two pages at once, on the ipad i prefer one larger size page as long as i can flip pages quickly enough. i tried my 600 a few weeks after using the ipad and i could feel time creep by as i waited for those screen refreshes.
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