at first switched to R->L; more recently back to L->R
I read with a standard Sony cover (without the built-in light), and usually open in my left hand, turning pages with my thumb on the buttons. But, sometimes I like to use the screen--maybe the lighting conditions are such that I'll hold the reader two-handed, for example, or when reading in landscape mode. Then I am more likely to use screen gesture page turning, usually with the thumbnail on my right hand.
At first I changed the gesture direction from the default L->R to R->L, because that felt more "natural", as if I were turning the page of a book. (I initially found the "default" to be a bit "odd" as in "counter-intuitive." But this changed.)
Later on I experimented the other way (Left->Right) and found that, for me, ergonomically, I used much less energy with a very slight "thumb-scratch" at the edge of the screen, typically near the lower right corner.
However, I probably rely on the buttons for page turns 90+% of the time. I like having the screen for situations when the buttons are not as convenient; and I agree with the comments that some additional page-turn buttons at other key spots would have been nice.
Cheers!
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