I run it under Windows 7 64-bit. There was an old thread around here with some tips/tricks for installing it on Vista, which pretty much applies to Windows 7 as well.
You don't want to install it into the C:\Program Files directories, but rather somewhere else. That'll help with permissions issues. There are also a couple libraries you need to register by hand from a command prompt running as Administrator. If you need to use PDFCreator, there is a trick for installing that as well.
It's all in the thread. I'll see if I can find it. I usually have to refer back to it whenever I need to re-install my system, so you'd think I would have it bookmarked by now. Oh well.
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