I've used the Iliad and DR1000 by Irex and the Astak 5" EZReader PocletPro. For PDFs, I use the DR1000 due to screen size. For general reading of anything other than PDFs, I use the PocketPro and am very happy with it. Before I bought it, I thought I'd have issues with the small screen size, but I don't have any. It's now my favorite for anything other than PDF and I get great battery life to boot.
Even for reflowable PDFs I prefer the DR1000 because a lot of times the reflow looks bad.
My $0.02.
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