Re: Font sizes:
If you are reading correctly formated pdfs on a windows devise using adobe reader, there is unlimited enlargement of the font using reflow and magnification. Lit files have to be reformatted to get sizes past a certain point as do Sony ebook files.
Re Tablet pc's:
Windows Tablet edition is XP Pro with pen input support. While most reader programs may have limits on how the font size/style can be manipulated, there are settings in XP to help with vision issues, and if those are not enough, other programs are available to do even more.
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