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One of the consequences of Geo-restriction in books, leads to searching out alternative authors .... hence ....
Darrell Bain - Pet Plague Trilogy -
book one is a separate story to books 2 & 3; but the trilogy explores the consequences of genetic manipulation, especially when applied human/animals. Not strictly "end of the world", but "end of the world as we know it!".
Some of his other works are good, too ....
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