I prefer Mobipocket because that was the first format I used, so it's the one I'm most comfortable with. Also, with the MobideDRM plugin for Calibre, the DRM removal is completely invisible and painless. ADE ePUB comes in a close second, but it loses out to Mobi due to the extra step required for DRM removal (which is ALWAYS my first step whenever I buy a DRMed book).
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