Well, I have a 505 and I think it's great. But, I haven't ever had my hands on a Nook so it's impossible for me to know how it compares.
I'd advise the same as I always advise - try to get a hands-on trial of each and go for the one that you feel suits your needs best. If I've learnt one thing from reading these forums, it's that personal preference makes a huge difference with these devices.
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