So here is a test ePub I've thrown together. 3 pages with the same image resized to 3 different screens: 6" Readers (505/nook/etc), Sony-900, and iRex 800 in that order.
What I'm noticing is that the iRex is definitely ignoring pixel sizes. If you set the font size to medium, it will respect them, but not on the default setting of small.
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