Originally Posted by markbot
I think that the type of people who buy the iPad wouldn't implement the color inversion even if it might solve the eye strain problem for long-read sessions.
I'm trying to imagine the iBooks little page turning animation with a black and green screen.
As for eye strain. At work, I make sure my panels are at the max refresh rate, the backlights are almost off and the contrast is way up. The applications I have where I can set the colors have a dark gray background and very light gray text. I also have a strong, full spectrum light behind my head. It seems to help me get through the day.