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For me it only depends on the width of the page. If the page is pretty wide, my eyes will tend to wander from a line to the other. Having a space will help to stay focused on a particular line with more ease.
I believe this to be one of the factors why multiple columns were used in wide format printing. If everything was printed the whole width, they'd have had to put spacing lines. With multiple columns they did'nt and were able to cram more text on a page. And since printing was difficult and expensive...
The reader is not wide enough to justify the need for an extra line other than esthetics.
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