Could be any or all of the following:
1. Your computer is too slow or it is doing something else at the same time that slows it down. Reboot and try again, before starting any other tasks. Try on another computer.
2. The .epub file is corrupt. Try editing another file and see if that is faster.
3. You are working with the file stored on slow memory. Copy the .epub to the desktop and edit it there.
4. The Sigil install is bad - reinstall and try again. Perhaps even a more recent version.
5. Something else...
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