Yes I have tried just removing the Mac files with mixed results. The files are embedded in almost every folder within the Reader's structure so it takes time to remove (not really an issue) and test after each instance, as a result I've found it's easier and quicker to just copy to a new desktop folder, format and re-install minus the Mac's. I've also encountered 'inbred' corruption between installed folders which has ended up putting the problem back onto the Reader ... so the folders are re-installed one at a time with verification of correct operation after each transfer; if the problem occurs after your last transfer simply break the folders down until you find the responsible file(s). Sounds a little long-winded but the most guaranteed way to restore normal operation.
Hope that helps?