Well, I use Word 2007 and the feature "Save as PDF" and it works very well. I load an ebook, format it as I want (for example 9 font size and 8 interline, 9x12 page size) and then "export" to PDF.
I think there is no appreciable quality difference between a "perfect" PDF done with latex than one "imperfect" done with Word (or other similar program) when it is being viewed in a reader...
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