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The Nook is the first mobile ADE-based device not to include a "full page" view as one of its PDF options. This was a mistake - in part because of screen-sized PDFs but also because a full page view can help with understanding the reflowed version.
In order to disable reflow for a given page you need to provide an element on the page that can't be discarded and can't be reflowed. Can pdftex draw a box around the text, e.g. in the page margin? That might work. If not, I have seen PDFs (and LaTeX) with DRAFT on a diagonal across the page in gray. This might disable reflow, and it might do so even if the DRAFT (or NO-REFLOW) was invisible, i.e. drawn in white or a pale gray that maps to white with 16 grayscales. Note that the DRAFT should be text, rather than an image. I have seen reflow discard full-page background images in some cases.
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