Showed the Nook to my wife tonight. Big mistake.
She absolutely loves it. As in, wanted to know how much it was and where was hers? In fairness she's a teacher and reads a lot so this isn't entirely unexpected but when I showed her the B&N online ebook store she about freaked. That and Cover Flow (she's also an iPhone convert) pretty much sold her on the spot.
I listened to a lot of her comments and didn't try to lead her along. She didn't have any complaints about brightness, the display, navigating the UI, or speed. (She's never used an ebook reader before.)