I have the Tumor books and Elk's Run on a Kindle DX. These are graphic novels, so readability is probably similar to manga. The Tumor books were great, but the Elk's Run book was almost barily readable, and that was on the DX. I'm nearly certain that you would find the Kindle 2's screen is just too small (even with the latest software upgrade).
Edit: I just looked at Daffy's images, and those didn't look too bad.
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