Same problem here (OSX 10.5.8) I renamed python in .../Contents/MacOS/ and tried to start in Terminal. Here is the error I got in Terminal:
LSOpenFromURLSpec() failed with error -10810 for the file /Applications/calibre.app.
and here is the error I got in system.log:
Nov 14 13:43:40 AlinsMacBookPro com.apple.launchd[115] ([0x0-0xec0ec].net.kovidgoyal.calibre[3955]): posix_spawnp("/Applications/calibre.app/Contents/MacOS/python", ...): No such file or directory
Nov 14 13:43:40 AlinsMacBookPro com.apple.launchd[115] ([0x0-0xec0ec].net.kovidgoyal.calibre[3955]): Exited with exit code: 1
does this help? BTW...many thanks for all your hard work on this great program!
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