You can get a pretty good idea of how it'll look using the "Full Screen Preview" mode in the Connect software (which you don't need to have a Reader in order to install). When I'm doing my book conversions, I rarely load them onto the "real" Reader; I use Connect to see how they look.
The only real difference between the Connect preview and the "real" Reader is that the "Table of Contents" in Connect (the "pop-out tab" on the right side of the screen) shows a lot more text than the real "Table of Contents" on the Reader does. The actual text pages themselves, though, are an excellent match in Connect and the Reader.
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