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I too primarily hold books at the bottom left so the transition to my Sony PRS 700 was super easy since there are page turn buttons right by the spot where your left thumb rests. It's also simple enough to move your hand up a little bit and use your thumb to swipe the touchscreen. The newer 600 model looks like it would work similarly. IMO the touchscreen makes page turning a non-issue since you can hold the reader in almost any position and still be able to turn pages with very little effort.
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