I read left-handed, like the OP, but I prefer to use my ebook readers without a cover - it adds too much weight. That is, if I'm out and about, I'll use a cover, but at home I just use a silicone skin.
Anyway, I've found the Kindle 2 to fit me best; the wide bezel makes it comfortable to hold. But you're canadian, so I guess it's not an option.
The Hanlin V3 (or Astak Reader) has buttons on the left that's also quite nice to use. It's also very light and easy to hold one-handed. It's a bit utilitarian of design, but overall quite nice.
The Sony 505's left back-and-forth button is also okay, but placed so far to the left that you end up holding the device more by your fingers and that can be a strain. It's definitely better in a cover. The buttons on the Sony 600 seems to be placed well for left-handed use and you can also swipe the touch screen - I've not tried one myself though.
The Cybook didn't work for me, because the button was placed to eth right. Impossible for me to reach when holding left-handed. And right-handed wasn't better, as I'd reach across the button (I have medium-large sized hands for a woman).
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