Spike has no MSG. "High flavor yeast" is nutritional or brewer's yeast. I don't think it's got MSG in it, although perhaps MSG is derived from a different kind of yeast. My husband uses both extensively, and he's allergic to MSG.
Spike is a savory seasoning, a blend of over 50 individual spices, so it's hard to match it--but shouldn't be too hard to substitute for it. Salt with flavor attached. For the recipe mentioned here, I'd probably mostly use salt, with some onion, garlic, and oregano. Could add other meat-flavoring herbs, if you like. I suspect the salt & onion are the most important parts.
My husband, who is the cook in the family, is currently sleeping; I nudged him to ask what to substitute for Spike. He suggested mailing a jar of it, and fell back asleep. While I'm not opposed to the idea of spreading the Spike-love beyond the US borders, I doubt that it would get there in time to be useful for making this particular batch of marinade.
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