I guess the problem I've always had with page numbering in a fiction ebook is that if I'm so bored by the story that I feel compelled to discover just how far I've read and how far it is to the next chapter - then that's a good sign the story isn't worth the read.
There are far too many GOOD novels out there which suck me into the story deeply enough that I don't even really notice what chapter I'm on. And with all these great reads out there, I don't have time to waste on a story that doesn't reach that level.
Now if you want to talk about non-fiction books and page-numbering, well, the situation is completely different!
Derek