We recently purchased a 2006 Honda CRV. I started looking for a CRV that was 3 years old thinking that people would be trading in their 3 year leases and I would get a gently used car for a good price. My CRV had around 27,000 miles and cost $18,000. It was the last year they made that style of CRV which seems a little bigger than the newer model. I've been very happy with it.
We also have a 2003 Honda Odyssey that we purchased new and have never had any problems with it. With 3 kids and 3 dogs, the Odyssey is very roomy. We take it down to Florida at least once a year and are always grateful for the extra room.
We've stuck with Hondas because they are so reliable. We've actually bought a couple of slightly used Hondas and have been very happy with them.