i agree with you completely about the "hand agnostic" design !! and also about being able to use a liseuse with one hand only. these are important criteria for me too. that is what i appreciate about the opus ; to me, it's a huge jump ahead for hardware design precisely becomes it takes these criteria into account much better than, for instance, the gen3 design and all the similar devices.
i don't think the reading position should be imposed by the device, but chosen by the reader (i mean the person reading

) for their own comfort.