Quote:
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The Kindle DX features text-to-speech technology that can read textbooks aloud to blind students. The menus of the device are not accessible to the blind, however, making it impossible for a blind user to purchase books from Amazon’s Kindle store, select a book to read, activate the text-to-speech feature, and use the advanced reading functions available on the Kindle DX.
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So, it's not wholy unusable, but because you can't find the book and activate the TTS, it becomes unusable...
Oh, and I don't think you need a "one-click-does-all" button, but it would already help greatly if the menu items were spoken aloud too.