New,
You can increase the text size while you are reading by clicking on the plus button (looks like a magnifying glass with a + in the center) on the top/left hand side of the reader. If you want to increase the font size BEFORE you put the book on your reader using Calibre, you can only change this if your book is in rtf or txt format. You can open it in whatever word processing program you use on the MAC, select all the text and adjust the font size, save, and then upload. If you have a pdf writer, you MAY be able to adjust font size of pdf files, but I don't know about that. If your book is in lrf or epub then, as far as I know, you can only adjust the size 3x using the reader + button.
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