YOu guessed it, turning it off prevents accidental button pushing. I don't think there is any other reason to turn it off, but I'm not an expert. If you use the menu "Shut Down" command, the device will go into a low power usage state; I think that's recommended if you won't be reading for a week or more. I find starting up from Shut Down consumes as much power as leaving it in standby mode.
The ghosting was a bigger problem for me on the 500; I haven't seen it on the 505. If you change the page, it should wipe clear.
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