re: availability of content it's a Yes-And-No kind of a thing.
e.g. I'm a software engineer. I can find most computerbooks online. I can even download them for free (as in warez

)
can I read it on the reader?... sometimes
I agree with the TeleRead folks about the great need for an open universal ebook format.
On the other hand I've been trying to find The Slave from I.B. Singer and I couldn't...
A good bilingual Bible for the reader... also couldn't
I guess it greatly depends on what you're looking for.
I expect to see college textbooks and language books (with embedded audio) in the future formatted for the reader and similar devices.
sic.