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You are confusing native pixel anti-aliasing in Apple Retina mode and subpixel anti-aliasing (such as Cleartype) which uses coloured edges on fonts to effectively "sub-pixel" address to increase apparent resolution in horizontal direction on compatible displays. That type of subpixel addressing only works if the RGB stripes (or similar layout) is vertical.
Using physical pixels on a retina display (Apple only term) is not subpixel addressing.
At all resolutions using hinting on small fonts is important.
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