One advantage to downloading ePub from Kobo is that you don't need to install Kobo Desktop.
You can use the DeACSM plugin for ePub eBooks to download the ePub from the .acsm file and when setup properly, DeDRM will remove the DRM after the ePub is downloaded.
Another advantage is because calibre can make KePub on the fly, you have the choice of ePub or KePub for which you prefer to read. There is an option in the KoboTouch driver such that you can create a Y/N column for if you want KePub or not. I do this. I have a bit of code that allows me to decide what format I want.
IN the KoboTouch driver, in the second tab from the left, there is Template to decide conversion:. The code I use is
Code:
program: $#kepub == 'yes'
#kepub is the column name I've chose for my Y/N column.