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That works so poorly on ebooks, especially smaller screens, that I edit such docs or ebooks to have the parts as sequential paragraphs. Actually can be easier for the reader. Examples are epistolary chapters with two letters in two columns or two languages.
See also why tables often don't work.
You have no control over the user selection of model (size of screen and dpi), or font size, or margins or line spacing.
Even if you get the conversion to work, it's doomed. big tables or multiple columns only works for paper (or PDF intended for paper as oven screens aren't big enough for mulit-column PDF.
Summary: Mostly you need to avoid multiple columns, no matter how formatted, in source for true ebooks.
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