Not genres per se, but I like to switch between heavy/serious literature and more light reading. I can generally read a lot of serious literature in a row, but not lighter stuff I've found.
I read a couple of books in the Rivers of London series and it got quite boring, so I switched to some essays by Chesterton (what a breath of fresh air!) and then other stuff. But that (RoL) series also suffers from the Terry Pratchett syndrome of trying too hard to be funny in some sort of English/British way.
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