I edit lots of french ebooks, and I've never noticed such a thing (calibre 7.17, debian stable, x11).
I would suspect another soft or utility interacting with the behavior of the mouse. I had once, for example, qstardict interacting with the clipboard of LibreOffice, and only with this one.
For testing purpose, try to unload every utility working in the background, or, better, create a new user and load the editor in it.
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